This little list is an overview of the tools and mods that I use for a Witcher 2 playthrough. Unfortunately, TW2 isn't that mod-friendly.

The Tools

• Gibbed RED Tools

Mods - Bug Fixes

• Walls have ears and Suspect Thorak Bug fix replaced by PM-TW2UP
• Wild Hunt journal entries fix replaced PM-TW2UP
• Project Mersey - The Witcher 2 Unofficial Patch

Mods - Camera & UI

• Witcher 3 Icons

Mods - Models, textures, Overhauls

• Aen Seidhe Eyes
• Hiuuz's TW3 Triss Merigold
• More_Sexy_II and More_Sexy_III (though I didn't play with III)
• Sodden Scars for Triss
• Witcher 2 Tattoo Removal

Mods - Gameplay effects

• Faster Exploration Run Speed
• Maximum level 70 not 35
• Medallion Cooldown Reduced

Mods - Inventory

• Better Imported Items
• Mutagen slots
• Purchasable Mutagens
• Quickslot Potions

Mods - Cheats

• 3 talents per level + Dice cheat
• Toggleable Cat Effect with a Hotkey

References

• 3 talents per level + Dice cheat - https://www.nexusmods.com/witcher2/mods/863

• Aen Seidhe Eyes - https://www.nexusmods.com/witcher2/mods/948

• Better Imported Items - https://www.nexusmods.com/witcher2/mods/54

• Faster Exploration Run Speed - https://www.nexusmods.com/witcher2/mods/915

• Gibbed RED Tools - https://www.nexusmods.com/witcher2/mods/768

• Hiuuz's TW3 Triss Merigold - https://www.nexusmods.com/witcher2/mods/920

• Maximum level 70 not 35 - https://www.nexusmods.com/witcher2/mods/674

• Medallion Cooldown Reduced - https://www.nexusmods.com/witcher2/mods/722

• More_Sexy_II - https://www.nexusmods.com/witcher2/mods/808

• More_Sexy_III - https://www.nexusmods.com/witcher2/mods/950

• Mutagen slots (5 variations) - https://www.nexusmods.com/witcher2/mods/864

• Purchasable Mutagens - https://www.nexusmods.com/witcher2/mods/213

• Project Mersey - The Witcher 2 Unofficial Patch - https://www.nexusmods.com/witcher2/mods/981

• Quickslot Potions - https://www.nexusmods.com/witcher2/mods/740

• Sodden Scars for Triss - https://www.nexusmods.com/witcher2/mods/930

• Toggleable Cat Effect with a Hotkey - https://www.nexusmods.com/witcher2/mods/918

• Walls have ears and Suspect Thorak Bug fix - https://www.nexusmods.com/witcher2/mods/886

• Wild Hunt journal entries fix - https://www.nexusmods.com/witcher2/mods/885

• Witcher 2 Tattoo Removal - https://www.nexusmods.com/witcher2/mods/277

• Witcher 3 Icons - https://www.nexusmods.com/witcher2/mods/783

... to be continued