My game's missing loads of textures and objects

[MarioBath]

First of all, I use the Mod Organizer 2 and my game is not on my (C:) hard drive installed, it's on my SSD.  The mod manager is also installed on the same SSD and I went with the "portable" version, since I didn't want my MO2 mods, to be on another drive.
I'm not really sure why my Skyrim looks like this and I tried already the simple stuff, like reinstalling the whole game, disabling mods until it runs fine, deleting SKSE fully and replacing it with a fresh one.
Could be a SKSE problem, since it CtD when started it via MO2 after I disabled all the mods (except the script part of SKSE).
My MO2 crash dump folder is empty.

Skyrim SE runs just fine, if I start it via steam. 

I hope I provided everything I should have and thank you very much for taking the time to read my post!

EDIT: The game also crashes, when I start the normal launcher via the MO2

modlist.txt

[MarioBath]

Well, turns out my MO2 installation was corrupted. Prob. some left over files from my last time?
Not sure if I should deleted this post now, since somebody could possibly have the same problem.