Activation 'E' key not working

[Suludi]

You may have to go back to an earlier save when the E key was still working.

 

I was able to repair the issue once but only because I knew which plugin was broken. When I opened it in TES5Edit, I saw that all the activator keys had been assigned wrong. I still don't know how it happened but deleting that stuff from my mod solved the problem.

[bahamut2119]

The method i mentioned is infact the correct method i forgot about this while dealing with a issue i was having heres the same post i found awhile ago when i had your bug http://www.xboxachievements.com/forum/showthread.php?t=343333 and just for a quick lookup this is what it says:

 

 

i had the same problem 60 hours into the game, nothing i tried fixed it. 
after looking online i found a solution that worked for me and hopefully for others:

as i was already in whiterun (not sure if it HAS to be here) i went to the blacksmiths and waited for someone to start using something (in my case the tanning rack), i unsheathed my weapon and tried to use the tanning rack. the game tells me i cant use it because someone else is using it, i then put my weapon away and tried the forge and bam i can start using the tables/forge/etc again