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[Mod][XCL] U666's Drugs


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[XCL] U666's Drugs


A collection of non-X-Change drugs for Drug Framework 4

 

Author: usagitriplesix

 

U666 Drugs

These are my Drug Framework 4 consumables for X-Change Life.

 

Unlike ordinary X-Change pills, these drugs generally do not transform the user's gender. Instead, they apply temporary effects, modify an existing transformation, alter sexual function, or create other special conditions.

You can install as many or as few as you want.

 

IMPORTANT: Unpack This Download

The U666 Drugs collection ZIP is not a Mod Loader package.

Unzip it first, then install the individual .twee or .xcl drug files you want to use.

All drugs on this page require:

  • U666 Drug Framework 4

Some drugs also require:

  • U666 Effects CORE

The individual drug's Mod Loader metadata should warn you if a required dependency is missing.

 

Spike Fun

You do not need the Drug Framework Spike Registry merely to buy or use these drugs normally.

If you use Spike Fun, supported drugs can participate in its spiking systems according to their individual eligibility rules.

Not every drug can be selected for every kind of spike. Some are intended only for voluntary use, some require a particular body or situation, and especially dangerous drugs may be restricted to authored scenarios.

 

 


 

Available Drugs

Baby-Bomb™

A two-stage fertility treatment from Natalyne Biologics.

Baby-Bomb begins with a seven-day uterine priming period, followed by a fourteen-day peak-fertility period. Semen exposure during priming can interfere with the process, making this a drug where following the instructions actually matters.

It is intended for characters capable of pregnancy and will not start normally when pregnancy is disabled or an existing pregnancy has already been detected.

Requires: Drug Framework
Effects CORE: Not required
Optional: Pill Diagnostic Kiosk

 


Chill Pill™

Short-term pharmaceutical aftercare for when something else has pushed your libido too far.

Chill Pill suppresses arousal pressure from aphrodisiacs and libido-related effects, giving the PC some temporary relief.

It is not an antidote. Whatever is causing the problem remains active underneath the suppression.

Repeated use can build tolerance, and leaning on it too heavily can make the eventual rebound considerably less pleasant.

Requires: Drug Framework
Effects CORE: Not required

 


Cock-Up™

A temporary male enhancement drug from Rexor.

Cock-Up increases penis size while the user is male and also increases sensitivity. Frequent or prolonged use is a bad idea: overuse can cause headaches, reduced concentration, impaired orgasm control, and post-use size complications.

Requires: Drug Framework
Effects CORE: Not required

 


Confidence™

An instant confidence booster intended to complement a female-body transformation.

When taken while the PC is female-bodied, Confidence can temporarily apply Exhibitionist, making the PC much more comfortable showing off her body.

It is an instant modifier rather than a long-running drug course of its own.

Requires: Drug Framework
Effects CORE: Not required — uses XCL's existing Exhibitionist effect

 


Flirtatious Femme®

A social-confidence and flirtation drug marketed toward female-bodied users.

Flirtatious Femme temporarily applies Impulsive Flirtation, making it harder to keep flirtatious or provocative thoughts from slipping into conversation. It can also make the PC more comfortable with her current female state.

Additional doses can extend the course.

Requires: Drug Framework
Effects CORE: Not required

 


Hold-Out™ / Hold-Out™ Maxx

Male sexual-performance drugs from Rexor.

Hold-Out raises the PC's pleasure ceiling during sex, making it harder to climax and improving staying power.

Hold-Out Maxx is the stronger version and can repeatedly pull the PC back from the brink of orgasm.

Repeated use comes with a downside: overuse can leave the PC temporarily unable to climax through masturbation.

Requires: Drug Framework, Effects CORE

 


LactiFlow™

A grey-market lactation support drug.

LactiFlow maintains lactation while active and increases milk production. It is marketed as a practical lactation aid rather than a pleasure drug.

It does not directly increase breast sensitivity.

For that, see TenderTouch.

Requires: Drug Framework, Effects CORE
Optional: Pill Diagnostic Kiosk

 


Nymph-O

A powerful grey-market aphrodisiac built around the Insatiable effect.

Instead of simply adding a burst of arousal, Nymph-O makes desire keep coming back through persistent arousal floors and recurring pressure. Repeated exposure can deepen the effect and may leave lingering conditioning.

Nymph-O is deliberately not ordinary open-shelf merchandise by default, so installing it does not necessarily mean it will immediately appear beside the other retail drugs.

Requires: Drug Framework, Effects CORE

 


Sexual Overdrive™

An aggressive sexual-sensitivity enhancer from X-Perience.

Sexual Overdrive makes sexual stimulation more effective, makes orgasm easier, and supports increasingly rapid recovery for additional orgasms.

The manufacturer warnings against repeated dosing are there for a reason. Repeated active doses strengthen the effect and increase the risk of longer-lasting complications.

Requires: Drug Framework, Effects CORE

 


Penance™ for Her

An orgasm-denial drug marketed as a sexual self-control aid.

While the PC is female-bodied, Penance suppresses orgasm in most situations and limits how high pleasure can climb, while providing a small concentration benefit.

It does not provide the same orgasm-blocking effect while the PC is male.

Requires: Drug Framework
Effects CORE: Not required

 


Tabula Rasa™

An illicit identity-destabilization drug.

Tabula Rasa links orgasm with the Identity Loss effect. Multiple overlapping doses can strengthen the effect and create a risk that what began as a temporary problem becomes permanent.

Because of the severity of the consequences, Tabula Rasa is not normal retail stock and is not part of the broad random Spike Fun pool. It is reserved for supported authored/scenario use.

Requires: Drug Framework, Effects CORE

 


TenderTouch™

A focused breast-sensitivity enhancer from Velvet Pharmacology.

TenderTouch increases pleasure from breast contact. It does not cause lactation by itself, but if the PC is already producing milk, milking and other breast stimulation may become considerably more arousing.

Requires: Drug Framework, Effects CORE
Optional: Pill Diagnostic Kiosk

 


Xpansion X-Tender

A third-party transformation extender.

X-Tender increases the remaining duration of the PC's current transformation pill. It does nothing useful if the PC is not already transformed.

Do not confuse it with X-Change's similarly named X-Tend product.

When Spike Fun is installed, an additional X-Tender with Continue variant can also become available, combining the transformation extension with Continue-style climax behavior.

Requires: Drug Framework
Spike Fun: Optional support for the Continue variant

 


Yes™

SWP's People Pleaser effect in temporary drug form.

Yes temporarily applies People Pleaser, making it harder for the PC to reject requests, disappoint people, or simply say no when someone wants something from them. While active, it can also occasionally cost an Action Point.

Yes is not ordinary generic retail stock in the current setup; it is primarily available for supported authored and spiking content.

Requires: Drug Framework
Effects CORE: Not required — uses XCL's existing People Pleaser effect

 


 

Recommended Companion Mods

Knockoff Pharmacy

Recommended if you're using a selection of third-party drugs and pills.

Knockoff Pharmacy adds the Pill Poppa store to Paradise Mall and gives non-X-Change products a more appropriate place to be sold. Drug Framework products can be sorted into proper categories rather than mixed indiscriminately into ordinary transformation pills.

 

Pill Diagnostic Kiosk

Useful when you want to find out exactly what is currently affecting the PC.

Drug Framework tracks drug identity, duration, and effect provenance so the Diagnostic Kiosk can distinguish the drug itself from the effects it caused.

This is particularly useful after unidentified or spiked doses.

 

Spike Fun

Spike Fun uses these drugs as possible payloads for its various spiking scenes and scenarios.

The drugs still own their actual effects; Spike Fun is responsible for deciding when and how an eligible drug gets administered.

 


 

Current Drug Collection

  • Baby-Bomb™

  • Chill Pill™

  • Cock-Up™

  • Confidence™

  • Flirtatious Femme®

  • Hold-Out™ / Hold-Out™ Maxx

  • LactiFlow™

  • Nymph-O

  • Sexual Overdrive™

  • Penance™ for Her

  • Tabula Rasa™

  • TenderTouch™

  • Xpansion X-Tender

  • Yes™

 


  • Submitter
  • Submitted
    10/21/23
  • Category
  • Requirements
    Drug Framework 4 by U666, Effects and Side Effects COREs

 

Posted

I wonder if you'd like to make a drug that makes orgasms hard to achieve, but not impossible. Would make things interesting.

Posted
On 10/28/2023 at 8:11 AM, mijhy said:

I wonder if you'd like to make a drug that makes orgasms hard to achieve, but not impossible. Would make things interesting.

 

That's not a bad suggestion. Might want to throw that up on the Discord in one of the mod idea sections. I'm not sure what would be involved in making it work, offhand.

  • 1 month later...
Posted

Still get 3 errors on every new day. You can see them in debug screen. Type (debug:) after pressing ` to see it btw.

 

Line 209, (if: not (_drugCU's 1st's timer > 0))

 

Says that the array has 0 elements and it's trying to find one. Maybe you need a conditional check to see if the drug is actually active before this code block runs

Posted
On 12/23/2023 at 1:01 AM, mijhy said:

Still get 3 errors on every new day. You can see them in debug screen. Type (debug:) after pressing ` to see it btw.

 

Line 209, (if: not (_drugCU's 1st's timer > 0))

 

Says that the array has 0 elements and it's trying to find one. Maybe you need a conditional check to see if the drug is actually active before this code block runs

 

Oh, I had no clue that how to use that. I'll have to look into it.

  • 3 months later...
Posted

hello there, I have tried installing your newest version of the u666 pill mod seems to have issues with the Demo Framework mod.

 

something about: Datdude Demo Framework - conflicts with U666 Futillity + Calliente on(Work options) is that something that can be ignored or is it something that you need to take a look at?

 

friendly greetings from me

Posted
1 hour ago, danishplay said:

hello there, I have tried installing your newest version of the u666 pill mod seems to have issues with the Demo Framework mod.

 

something about: Datdude Demo Framework - conflicts with U666 Futillity + Calliente on(Work options) is that something that can be ignored or is it something that you need to take a look at?

 

friendly greetings from me

 

No, those are intentional conflicts to make this mod work.

Posted
8 hours ago, danishplay said:

hello there, I have tried installing your newest version of the u666 pill mod seems to have issues with the Demo Framework mod.

 

something about: Datdude Demo Framework - conflicts with U666 Futillity + Calliente on(Work options) is that something that can be ignored or is it something that you need to take a look at?

 

friendly greetings from me

 

I think it's okay; I haven't had any major issues, but I never really dug into the code.

I want to say what the drug does is allows your arousal to go up over the course of the work day. I think it's probably just a non-destructive [around], so it probably isn't an issue.

 

7 hours ago, ButchDiavolo said:

@emes, what mod is that Sebastian image from?

 

 

I don't know. I'm not sure who Sebastian is. Spike Fun has a bunch of AI-generated NPC images, but the names are somewhat randomly assigned.

Posted
5 hours ago, emes said:

 

I don't know. I'm not sure who Sebastian is. Spike Fun has a bunch of AI-generated NPC images, but the names are somewhat randomly assigned.

 

Sebastian is the pic in the download section of the file. It looks like he is your male pic ;)

 

Posted
12 hours ago, ButchDiavolo said:

 

Sebastian is the pic in the download section of the file. It looks like he is your male pic ;)

 

 

Oh! I didn't even realize...

 

That's probably from my AI Art Replacer...

 

 

The male version of Autumn.

 

  • 6 months later...
Posted

hey there I have just installed your newest U666 drugs mods, but it seems to dislike the confidence pill saying it needs a newer version, that the present one is 0.20, but it needs 0.21 or newer

Posted
3 hours ago, danishplay said:

hey there I have just installed your newest U666 drugs mods, but it seems to dislike the confidence pill saying it needs a newer version, that the present one is 0.20, but it needs 0.21 or newer

 

Confidence uses the Exhibitionist effect, which is in 0.21.1 but not 0.21.0. I think it'll still work if you install the Exhibitionist mod, though.

Posted (edited)

I thought I had the newest exhibitionist mod, but I could be wrong, I will take a look 🙂 

 

I had fallen a exhi-mod behind it seems, but the thing it says.

 

is  that ´does not support base game version 0.21.0, but needs 0.21.1 or newer, but I think the latest version of the base game. that came up on the 4th october says 0.21.0 so I am. a bit confused 🙂 

Edited by danishplay
Posted
1 hour ago, danishplay said:

I thought I had the newest exhibitionist mod, but I could be wrong, I will take a look 🙂 

 

I had fallen a exhi-mod behind it seems, but the thing it says.

 

is  that ´does not support base game version 0.21.0, but needs 0.21.1 or newer, but I think the latest version of the base game. that came up on the 4th october says 0.21.0 so I am. a bit confused 🙂 

 

The Exhibitionist mod should work with XCL 0.21.0 but will no longer be needed in XCL 0.21.1+ because it will be part of the main game.

 

If you have the playtest version, you might not need the mod, but for the public version, I doubt Confidence will work properly (might not cause any errors, though).

 

Posted
5 hours ago, emes said:

 

The Exhibitionist mod should work with XCL 0.21.0 but will no longer be needed in XCL 0.21.1+ because it will be part of the main game.

 

If you have the playtest version, you might not need the mod, but for the public version, I doubt Confidence will work properly (might not cause any errors, though).

 

Thank you for the information 🙂 

  • 1 year later...
  • 1 month later...
Posted

noticed with new XCL version when ever character takes a drug it won't load the drug i don't get any error it just won't load them after taking any drug

 

  • 2 weeks later...
Posted
On 12/31/2025 at 4:42 PM, Kyatinoa said:

noticed with new XCL version when ever character takes a drug it won't load the drug i don't get any error it just won't load them after taking any drug

 

I'm getting this too, and am unsure if its the new version of the game or a mod interaction that is causing it

Posted

also the icons for the drugs dont show up for my character under the character picture in the top left even after getting spiked, but the effects of some of them still show up in the drug diagnostic kiosk mod in the knockoff pharmacy

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