So far, everything's running smooth, no CTDs, no game freezes... Haven't noticed any issues in cells that would previously cause hiccups with the old framework (that was mostly due to my mods, I'm sure, oddly enough it happened in relatively unpopulated cells for some reason or other).
I decided to try out the creature animations from the updated framework with the debug spells...
Pretty much everything is on point-- that I'm seeing so far...
Tested Falmer, Troll, Dragon, Chaurus, Werewolf and wolf/dog...
Dragon sill has the issues of either being off-center or flipped (or both), but animation goes over well (much like from the "Bestiality" animation) posted here since it's the same animation structure, but now conveniently integrated into SexLab...
Dog animation seems non-functional. Wolves (and werewolves, oddly enough)- the animation for the victims seems to engage, but the aggressor animations for the beasts do not, they seem to just stand still & to the opposite direction of the victim.
Installed the "bestiality" mod just to see if it was an issue with the framework or my setup-- bestiality animation seems to trigger in full, but no change to SexLab variant.